Title: Characterization of Liquid-liquid Phase Separation by Millisecond Flashing Electrophoretic Separation
Dr. Wang obtained his BSc in Chemistry from Wuhan University in 1991 and his PhD from the Dalian Institute of Chemical Physics, Chinese Academy of Sciences in 1997. He had done his post-doctoral research at the University of Alberta, Edmonton, Canada, and joined the Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences (Beijing) in December 2005, where he is Professor of Bioanalytical Chemistry and toxicology. He developed advanced analytical technologies (UHPLC-MS/MS, qPCR, genome-wide sequencing) for characterization and functional study of DNA 5-methylcytosine and its oxidation intermediates and DNA N6-methyladenine. His study for the first time established a direct linkage among vitamin C, Tet dioxygenases, and DNA methylation. As a world-wide seminal work, he discovered new epigenetic DNA modification (N6-methyladenine) in high eukaryotes (Cell, 2015). He also has his expertise in ultrasensitive CE-LIF and UHPLC-MS/MS technologies for detection of carcinogenic DNA adducts and for study of DNA-repair proteins interactions.